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Funding This study was supported by grants from the Japan Society for the Promotion of Science (20H00509, 20H05876, and JPJSBP 120207405 to KH), AMED-Crest (20gm1010004h0105 and 20gm1310009h0001 and to KH), and The Naito Foundation (KH)

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Figure 1 4.1 SCFAs improve the glucose and lipid metabolism disorder Sterol-regulatory element-binding protein 1c (SREBP-1c) is a nuclear transcription factor located in the liver and can regulate the expression of related enzymes such as TG, TC and fatty acids (Lazarevi et al., 2019)