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10.1172/JCI12568 65 KongY.ChenH.HuangX.ChangL.YangB.ChenW

As mentioned earlier, NF-B inhibition increases ROS levels

Researchers at the University of Texas first characterized 5-amino-1MQ (5-amino-1-methyl quinolinium) in 2017 while searching for ways to inhibit nicotinamide-N-methyltransferase (NNMT) [1]

pretreated with aqueous-methanolic(Compositae) (500 mg/kg) also had the hepatoprotective effects by reducing ALT and AST levels, and inhibiting microsomal drug-metabolizing enzymes (Gilani and Janbaz, 1995a)