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Non-enzymatic Antioxidants Ascorbic Acid Ascorbate is taken into account a potent antioxidant thanks to its ability to donate electrons in an exceedingly wide selection of enzymatic and non-enzymatic reactions

To investigate the drug release kinetics of HFn@M/R under pathophysiological conditions, phosphate buffer saline (PBS) containing 1 mM HO and 0.5% Tween 80 were employed to simulate cerebral oxidative stress, while PBS buffers at pH 5.0 and 7.4 were implemented to mimic physiological environments

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strikingly, we found a significantly lower number of neural NESTIN-positive (NES + ) cells in Mettl9 KO cultures compared to the Mettl9 WT (parental line, E14), as shown by immunofluorescent (IF) staining of NSCs and cell counting, at DIV6 (Fig