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investigated a novel Pickering emulsion gel (APEG) loaded with oxaliplatin (OXA) and the LDHA inhibitor GSK2837808A (GSK) to confirm that the combination formulation can effectively enhance drug delivery efficiency and boost anti-tumor therapy by activating the tumor immune microenvironment and increasing the infiltration of CD8 + T cells (196)

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To effectively target ferroptosis in OA, both the induction of ferroptosis by immune mediators and the adaptive changes of metabolic reprogramming must be considered

We first measured GNMT activity in these cells by quantifying secreted sarcosine in the cell culture media using the sarcosine oxidase assay ( Figure 5B )