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Description

To investigate whether the DBAN-induced S phase perturbations activate the checkpoint, we synchronised a checkpoint-defective rad3 tel1 double mutant (Tel1/ATM is the second checkpoint kinase besides Rad3/ATR) in G2 and released cells into medium with or without 10 M DBAN

This study will provide further insights into the action of NCX 470 on key AH parameters and its potential as a treatment for IOP management in glaucoma patients