nadph and glutathione levels gliomas Frontiers A cell state-specific metabolic vulnerability

Electron microscopy of AZT-treated striated skeletal muscle from rats, and AZT-, ddC-, and 2,3-dideoxyinosine ( didanosine or ddI)-treated human hepatocytes show widespread mitochondrial swelling with poorly organized cristae (Lewis et al., 1992

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To further support the observations and conclusions, expression levels of the counter-selectable gene GAP1 and genes involved in GSH synthesis were determined by RT-qPCR in the pGSH1-GAP1 strain

doi: 10.1007/s10555-017-9698-5 34 JagannathanSVadNVallabhapurapuSVallabhapurapuSAndersonKCDriscollJJ