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Furthermore, high glucose upregulates the TGF-/Smad3 signaling pathway, promoting podocyte EMT and extracellular matrix (ECM) deposition, thereby exacerbating glomerular injury (Yasuda et al., 2021)

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A probable solution to this situation will be development of new diagnostic methods that will allow to predict the emergence of cataract long before the manifestation of its clinical signs and to start early preventive treatment

These findings further suggest that C75 improved endothelial function, leading to the restoration of erectile function