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Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal

The recent discovery of the small molecule N6F11, which binds the tripartite region of Trim25 and promotes proteasome-degradation of GPX4 in pancreatic cancer cells, while sparing immune cells and the anti-tumoral response of the microenvironment, could represent a major clinical breakthrough for the use of GPX4 inhibitor/degrader [61]

Regular intake of 2 g per day for at least two weeks can produce a small but significant decrease in BMI (~1.5%)

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