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Host drug-metabolizing enzyme expressions decrease toward the ileum and colon, whereas microbial density increases from approximately 1010 cells/g in the proximal small intestine to 1010 cells/g in the distal ileum and 1010 cells/g in the colon 104,105

Not to be used in cases of dehydration as a substitute for an oral rehydration solution

For example, studies have found that ID and IDA lead to a significant reduction in GSH-Px (a member of the GPX family) and GSH-R activities, indicating a compromised antioxidant defense system (122)

Here we have addressed this issue by developing a suite of LC-MS/MS methods that enable the sensitive and simultaneous quantification of H 2 S, RSS , RS(S) n S and GSS