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In particular, inhibitors specifically designed to interfere SIRT2-GCLC association and subsequent GCLC activation may be utilized to enhance tumor treatment efficacy while decreasing the toxicity to normal cells, which has the potential to ultimately improve the prognosis of cancer patients

By combining viral tracing, in vivo microendoscopic calcium imaging, and wireless optogenetics, we characterized the functional organization of a neural circuit connecting glutamatergic neurons in the paraventricular nucleus of the hypothalamus (PVN Glu ) to acetylcholinergic neurons in the DMV (DMV Ach ) to the small intestine

GeroScience 45, 35293548

UC carries a higher risk of developing colon cancer if not effectively treated, ultimately contributing to severe threats to life [1, 2]