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The IMQ-induced psoriasis mouse model was developed according to previously established methods

Despite advances in antimicrobial therapy and supportive care, sepsis continues to result in high morbidity and mortality, with an estimated 48.9 million cases and 11 million deaths worldwide in 2017, accounting for nearly 20% of all global mortality, disproportionately affecting low- and middle-income countries (Rudd et al., 2020)

The pathophysiology is incomplete transmission of intra-abdominal pressure to the bladder neck (where the bladder meets the urethra.) Baseline bladder pressure 10 cm H20 baseline urethral pressure 50 cm H20 1

198 (5): e44e68