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One of the main pathways through which oxidative stress causes permanent damage to melanocytes appears to involve the mitochondria, whose DNA is particularly fragile

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Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence

4c,d), indicating that LTC 4 activity is mostly intracrine, in contrast with LTC 4 S-generated LTC 4 in mast cells, which mainly acts on external target cells