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While the 10.612.8% mean weight reduction at 24 weeks was clinically significant, the risk-benefit calculus for a chronic weight loss medication with sympathomimetic cardiovascular effects didnt meet regulatory safety thresholds

Doses typically 300-500 mcg/day subcutaneously, often cycled 4-6 weeks

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Molecular and cellular actions of a structural domain of human growth hormone (AOD9401) on lipid metabolism in Zucker fatty rats Journal of Molecular Endocrinology, 2000 Dec, Volume 25 (Issue 3), Pages 287-98