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and WO 99/51642) and wherein the variant retains the ability to bind antigen

Lang et al., 2015b)

Future studies should focus on this approach

In order to establish NAD + -boosting interventions as credible therapeutic options, it is imperative that large-scale randomized controlled trials with longer durations, stratification by disease etiology, and liver-specific endpoints be conducted with utmost urgency (Dellinger et al