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Molecular Characteristics Complete Specifications: CAS Registry Number: 170851-70-4 Molecular Weight: 711.85 Da Molecular Formula: CHNO Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH Peptide Classification: Synthetic pentapeptide, growth hormone secretagogue Appearance: White to off-white lyophilized powder Solubility: Water, bacteriostatic water, phosphate buffered saline The peptides compact five-amino acid structure incorporates several key modifications that contribute to its unique properties

Effects on gene expression Transcriptomic studies in cells exposed to GHK-Cu have reported broad changes in gene expression affecting genes involved in collagen and matrix synthesis, antioxidant defense (including superoxide dismutase, catalase, and others), DNA repair, immune signaling, and cellular metabolism

For the IV regimen, a loading dose of 150 mg/kg in 200 cc is given for 15 minutes, followed by 50 mg/kg in 500 cc over 4 hours and then 100 mg/kg in 1000 cc over 16 hours

Rhamnetin interferes with EMT by targeting key transcription factors and signaling pathways associated with this process