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More recently, it has been observed that certain agricultural chemicals like rotenone and paraquat, when administered systemically, can replicate specific PD features in rodents, likely through oxidative harm (Lal and Chopra 2024)

( A ) LocusCompare plot of a pleiotropic disease locus mediated by various microbial genera, including Ruminococcaceae UCG009 (top), Ruminococcaceae UCG002 (middle), and Bifidobacterium (bottom), for their colocalization with schizophrenia GWAS and ATG13 locus in the transverse colon