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Both are not able to cope with larger hydraulic loads

Porosities in MBG could hypothetically be filled with the resin phase of the RBCs in the unpolymerised state and remain interlocked in this position after polymerisation

Possible side effects include: Mild pain, redness, or swelling at the injection site Headache or dizziness (usually transient) Nausea (uncommon) Hypokalaemia (low potassium) during initial treatment, particularly in severely deficient patientsthis is rare but may require monitoring [1] [5] When to seek medical advice: Serious adverse reactions are extremely rare

Acknowledgements We thank Elisabeth Rushing (Institute of Neuropathology, University Hospital Zurich) for support with the analysis of histological sections and Friedhelm Bladt and Frank Jhrling (Merck, Darmstadt, Germany) for providing EMD1214063 and for helpful discussions