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Saudi J Biol Sci 27(7):17101716 Boesch-Saadatmandi C et al (2010) Effect of quercetin on paraoxonase 1 activitystudies in cultured cells, mice and humans

Traditional ferroptosis-targeting drugs mainly include iron chelators like deferoxamine and deferiprone, antioxidants such as glutathione and vitamin E, and Nrf2 activators including sulforaphane and curcumin, all of which have shown promise in mitigating liver damage (see Table 1)

Modulations of hMOF autoacetylation by SIRT1 regulate hMOF recruitment and activities on the chromatin