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Description

Peroxiredoxin II E PRXs are antioxidant enzymes that catalyze the reduction of hydroperoxides into alcohols using a strictly conserved cysteine (i.e

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Thus, by inhibiting EndMT and TCF12 downregulation, NAC alleviates both increased perivascular collagen deposition and decreased interstitial collagen, restores cardiac collagen distribution balance, and reverses the cardiac function decline caused by PD-1 inhibitor