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Klatzo I, Wisniewski H, Streicher E (1965) Experimental production of neurofibrillary degeneration

However, FINGER enrolled at-risk individuals without cognitive impairment, making it a prevention rather than treatment trial

In experiments involving a mouse model of skin aging induced by D-galactose, treatment with higher concentrations of sea buckthorn PCs (50 and 100 mg/kg) led to an increase in TGF-1 levels within the skin tissue and the upregulation of Smad3 expression