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Age-related reductions in NAD + levels and sirtuin activity are contributing factors in the pathogenesis of a wide variety of cardiovascular and metabolic disorders, including atherosclerosis, endothelial dysfunction, acute cardiac syndromes, cardiomyopathy, hypertrophy and heart failure, arrhythmias, hypertension, metabolic syndrome, obesity, fatty liver, diabetes mellitus, and dyslipidemia [17]

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Preclinical research utilizes BPC-157 to examine peptide-mediated cellular communication, extracellular matrix dynamics, and regulatory signaling under controlled laboratory conditions

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