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Accumulated hepatic lipids, formed either by DNL or from free fatty acids, have been linked to the onset of hepatic insulin resistance

So, next time you slice into a cool, juicy watermelon on a hot day, remember that you're not just satisfying your thirst

These adaptive immune escape mechanisms do not occur uniformly but evolve alongside tumor cell heterogeneity, further restricting durable immune control and reinforcing resistance ecosystems established by stromal and metabolic protection (147, 148)