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neoformans Bone marrow derived macrophages (BMDMs) were isolated from BALB/c mice and differentiated at 37C with 5% CO 2 for 7 days in media consisting of DMEM, 10% FBS, 1% nonessential amino acids, 1% penicillin-streptomycin, 1% GlutaMAX (Gibco, 35050061), 1% HEPES buffer, 20% L-929 cell-conditioned supernatant, and 0.1% 2-mercaptoethanol 34

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169,389 SIRT1 is responsible for the histone acetylation patterns, including the H4K4ac, H3K9ac, H4K16ac and H1K26ac, associated with tight chromatin compaction

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