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First, find out how the lack of vitamin B12 affects weight gain

By interacting with both the glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors, Tirzepatide effectively regulates appetite, decreases food consumption, and enhances insulin sensitivity, ultimately leading to significant reductions in body weight

If you experience any concerning symptoms while taking B12 supplements, report them to your healthcare provider and consider reporting suspected side effects via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)

Women who may become pregnant should take a supplement with folic acid to prevent serious birth defects