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Both systems are ubiquitous in the cytoplasm, increasing the likelihood of ROS being deradicalised the further they travel from their source, and thereby helping constrain ROS-S spatially

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A randomized phase 2 study of trastuzumab and pertuzumab (TP) compared to cetuximab and irinotecan (CETIRI) in advanced/metastatic colorectal cancer (mCRC) with HER2 amplification: SWOG S1613