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If you are concerned about your risk for this condition, or if you have symptoms that suggest GSTT1 deficiency, you may want to consider getting a genetic test

These drugs mediate the release of DAMPs following hepatocyte injury, which are sensed by, for example, Kupffer cells (KCs), activating innate immune receptors to trigger intracellular events leading to the release of pro-inflammatory mediators, cytokines, and chemokines, and then recruit neutrophils and monocytes to the blood in a sterile inflammatory process

6.4.2 Novel microbiota-targeted therapeutics The development of novel therapeutics based on gut microbial mechanisms is emerging

For more information: www.rsna.org Related Content