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Lactate suppresses macrophage pro-inflammatory response to LPS stimulation by inhibition of YAP and NF-B activation via GPR81-mediated signaling

10.4067/S0718-95162013005000054 124 NathS.PandaP.MishraS.DeyM.ChoudhuryS.SahooL.et al

Liao, S

The mechanism underlying RIRI involves an initial phase of acute hypoxia (ischemia) caused by blood flow interruption, followed by a second phase of reperfusion injury when blood flow is restored, which exacerbates tissue damage