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Support was also provided by the USDA National Institute of Food and Agriculture grant 2016-67013-24581 to the American Chestnut Foundation

Taurine is a sulfur-containing amino acid found throughout the body

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Large hydrophilic chelators, such as DFO (a highly polar molecule with a molecular weight of 560 Da), exhibit poor BBB permeability when administered intravenously, remaining in the circulation and extracellular space, while only minimal amounts can cross into the brain parenchyma