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This approach has been recently successful in the therapeutic repositioning of the antiulcer drug cimetidine to lung adenocarcinoma and the anticonvulsant drug topiramate to inflammatory bowel disease [49, 50]

While proteins can contain hundreds or thousands of amino acids, peptides typically include between 2 to 50 , giving them the ability to act as precise signaling molecules in the body

This interference renders gluten peptides in depolymerized state, making them more water soluble which facilitates their proteolytic cleavage and thus imparting the required dough rheology [87]

Combining maintenance injections with ongoing programs like bioidentical hormone replacement therapy (for patients with hormonal contributors to weight gain) creates a long-term strategy for staying at a healthy weight