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Hydrogen peroxide induces autophagic cell death in C6 glioma cells via BNIP3-mediated suppression of the mTOR pathway

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Moreover, film samples were subjected to a photo-oxidative process under UV irradiation up to 11 hours and the oxidation level was monitored by means of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI TOF MS)

Figure 3 3.4 Epigenetic and signal transduction effects The regulation of epigenetics and the manipulation of signal transduction pathways have emerged as a fundamental mechanistic basis by which natural agents can exert strong anti-cancer effects in breast cancer, affecting the various stages of tumour development (initiation, progression, metastasis), and response to therapy by targeting diverse interactions between gene expression, chromatin structure, and intracellular signalling elements (198)