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Cockshell SJ, Mathias JL

[90] have documented lipolytic activity of ZAG and reductions in body fat mass during treatment of mice for 15 days with ZAG

Due to the fact that ACTL6A did not regulate NRF2, we could reach the conclusion that ACTL6A functions in conjunction with NRF2 to regulate GCLC expression at the transcriptional level