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USA 109 , 1634816353 (2012)

Ostojic, S

Additionally, TTM inhibits TNF--induced activation of NF-B and AP-1, leading to the suppressed expression of adhesion molecules (VCAM-1 and ICAM-1) and the chemokine MCP-1

Numerous in vitro studies show that ITCs induce apoptosis via both intrinsic and extrinsic pathways (108)for instance, through caspase activation (109), mitochondrial dysfunction (110), and oxidative stress generation (111)