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Pharmacodynamics of cisplatin-loaded PLGA nanoparticles administered to tumor-bearing mice

The gyroid, characterized by the highest number of layers, displayed the best photocatalytic activity, with a 43% increase in the reaction rate constant compared to the wheel geometry at 10 wt% TiO 2

A significant increase in hepatic STAT3 phosphorylation and acetylation and binding of FXR to Stat3 promoter, as well as decreased apoptosis markers by flow cytometry (FAS, caspase 8 and caspase 3), were present in FXR agonist/DDC mice compared to DDC mice