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However, bacterial biofilm in chronic wounds may cause irreversible bacterial adhesion, leading to persistent inflammation, tissue damage, and ongoing infection [43, 45, 46]

Given that EtOH-induced mitochondrial dysfunction and ER stress are intimately involved in the pathogenesis of ALD, future studies to examine these pathways under the current experimental setting will provide important mechanistic information underlying the protection seen in GCLM KO mice

Other common side effects include: Sun sensitivity

Results can be long-lasting if maintained with sun protection, healthy habits, and occasional maintenance sessions