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A typical assumption for the expected body weight for participants lost to follow up would be that these participants, on average, weigh the same at the end of the trial as comparable participants (by age, sex, occupation, family structure, etc.) who discontinued treatment at a similar time, but remained in the trial and thus had a final weight measurement
Here are some factors that can affect how quickly you notice results: Severity of Deficiency: Individuals with mild deficiencies may experience quick relief, but those with very low B12 levels might require several doses before a noticeable difference occurs
Hydroxocobalamin, which the body retains longer than cyanocobalamin, often allows less frequent dosing once levels stabilize
