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In a model mouse with autism-like behavior induced by prenatal exposure to a cafeteria diet, ADF increased anti-inflammatory CD206 + microglia in the hippocampus, reduced ER stress markers (BiP, ATF6, p-JNK), and improved social interaction

Prelimbic cortical injections of a GABA agonist and antagonist: in vivo quantification of the effect in the rat brain using [(18)F] FDG MicroPET

Because biosynthetic and degrading factors for glycogen, e.g., glycogen synthase kinase 3 (GSK3), glycogen synthase (GYS1), and phosphorylase (PYGM), are all reduced in dysferlin-deficient muscles (Fig 3F), the net effect on glycogen homeostasis is difficult to predict

The physicochemical stability of BPC-157 across various biological environments may contribute to its apparent safety profile, as the peptide appears to be well-tolerated when administered via different routes including oral, subcutaneous, and intramuscular administration