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Photoredox dearomative [3+2] cycloaddition of pnitrophenol with electrondeficient alkyne forms spironitrooxindole scaffold

When cells undergo ferroptosis, cell mitochondria become smaller, membrane density increases, and the number of cristae decreases, accompanied by increased cytoplasmic lipid peroxidation and increased levels of reactive oxygen species (ROS) [16, 18, 21]