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Drp1 is a direct target of Cdk5, and Cdk5-mediated phosphorylation of Drp1 at Serine 579 regulates A1-42 induced mitochondrial fission and neuronal toxicity

It also causes the skin to lighten by converting melanin to a lighter color and deactivating the enzyme tyrosinase, which helps produce the pigment 2

However, literature evidences suggest possible in vivo repression of GLNS by GlnR, a transcriptional regulator of nitrogen metabolism whose repressor activity has been observed in low-GC containing Firmicutes, including Lactococcus lactis 60 and Streptococcus pneumonia 61 under nitrogen excess condition

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