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In: Nat Rev Drug Discov

In order to inhibit NADPH oxidase we treated human PMNs with DPI prior to challenging with yeast cells

Systemic inflammation driven by diet and gut microbiome imbalance can worsen nerve pain, slow tissue healing, and reduce the effectiveness of regenerative therapies

In a rat model of DOX-induced cardiotoxicity, it has been unequivocally demonstrated that DOX induces the production of ROS and transforming growth factor-beta (TGF-), thereby promoting the transformation of cardiac fibroblasts into myofibroblasts (Tian et al., 2024)