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Queiroz for critically reviewing this manuscript

While urolithin A may be able to promote better mitochondrial health by supporting mitophagy,7 there currently isnt any research to suggest that the compound could benefit primary or genetic mitochondrial diseases (e.g., Leigh syndrome, Kearns-Sayre syndrome, Leber hereditary optic neuropathy, etc.).16 Some experts suggest that it could be worth investigating whether mitophagy activation could act as a novel strategy to treat these diseases, but that research hasnt been conducted yet.17 18 19 When that happens, well update this information

also investigated off-label to support endogenous testosterone alongside TRT protocols

It can indirectly affect menstrual cycles by regulating blood sugar levels and disrupting hormonal balance, which may lead to changes in menstrual patterns