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3.1% with placebo) in people with obesity without diabetes, the highest reported among approved obesity pharmacotherapies [27]

Additionally, exosome miRNA-126, which targets PIK3R2, has shown promise in preclinical models of pancreatic cancer by suppressing angiogenesis, providing a potential non-invasive alternative to traditional anti-VEGF therapies (58, 59)

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These progenitor cells have been identified in multiple species, including humans, rats, and pigs [36]