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Optimal clinical management of children receiving dietary therapies for epilepsy: updated recommendations of the International Ketogenic Diet Study Group

By activating SIRT1, resveratrol modulates gene expression associated with aging, inflammation, and metabolic health (Gao and Tollefsbol 2015

These data support an effect of IL-13 to decrease total and reduced GSH through high 15LO1, PEBP1, and GPX4 activity, which is partially compensated by (a) increased expression/activity of SLC7A11 to enhance new intracellular GSH production and (b) increased export of GSSG

Indeed, these molecules, derived from the enzymatic and non-enzymatic peroxidation of fatty acids, exhibit a reactive carbonyl structure, which makes them highly reactive electrophilic species and they are formed at proximity of mPGES-2 localization (Farmer and Mueller, 2013)