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Earlier studies proposed that the cation transporter of low sensitivity, divalent metal transporter 1 (DMT1), is involved in intestinal zinc uptake (Gunshin et al., 1997[173])

Quetiapine levels fell below the detection limit

Given the conserved chelating properties of transition metal complexes, existing clinical metal chelators can be repurposed and optimized for targeted platinum chelation, with priority given to strategies that reduce platinum accumulation in normal tissues while preserving intratumoral platinum concentrations