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Mouse and human studies have found that intranasal insulin reduces central nervous system inflammation and improves cognition by reducing proinflammatory cytokine levels and oxidative stress, and boosting antioxidant levels and mitochondrial functioning

1 Introduction Epithelial ovarian cancer (EOC) accounts for approximately 95% of ovarian cancer incidence, and is a leading cause of gynecologic cancer mortality worldwide ( Folate receptor alpha (FR), encoded by the FOLR1 gene, has attracted considerable interest due to its high expression in several cancer types including those of lung and breast