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Importantly, downregulation of PLSCR1 also suppressed the expression of P-gp and MRP1, two key resistance proteins regulated by the MAPK pathway [38, 39] (Fig

The Sinus-Brain Connection Paramount to the sinuses being the perfect breeding ground for mold to colonize, their proximity to the brain contributes to neuroinflammation

doi: 10.3389/fmed.2025.1629957 Received 16 May 2025 Accepted 12 August 2025 Published 02 September 2025 Volume 12 - 2025 Edited by Yun Shen, Pennington Biomedical Research Center, United States Reviewed by Mohak Jain, Sir Sayajirao General Hospital Medical College, India Suma Wirawan, Universitas Mahasaraswati Denpasar, Indonesia Updates Copyright 2025 Hou, Tong, Yang, Zhou, Fu, Gou, Xi, Liao, Li and Zhu

27 A decision whether or not to continue PPI longer term should only be taken once cure of H