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I wonder if it was also difficult for his father

NS indicates not significant

doi: 10.1080/21655979.2021.2010369 65 LiSLiYWuZWuZFangH

Slightly positive or near-neutral zeta potentials (approximately 10 to +10 mV) are generally preferred for systemic administration because highly cationic particles can strongly bind to the negatively charged endothelial glycocalyx and plasma proteins, causing aggregation, complement activation, and membrane damage (120)