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Vettermann, C., Herrmann, K

Although there is little evidence of interaction between iGluRs and mGluRs receptors, a dynamic interaction between the C-terminal domain (CTD) of mGluR5 and NMDAR (GluN1a/2B) receptors have been reported in the human embryonic kidney (HEK) 293 cells using bioluminescence resonance energy transfer (129)

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The mean changes from baseline of Hb A 1c at d 28, and d 56 were: 0.16% 0.07 (1.71 mmol/mol) and 0.21% 0.09 (2.24 mmol/mol) for the ARA 290 group and 0.01% 0.07 (0.14 mmol/mol) and +0.21% 0.08 (+2.24 mmol/mol) for the placebo groups respectively (Figure 1