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(6) Mason C, Xiao L, Duggan C, Imayama I, Foster-Schubert KE, Kong A, Campbell KL, Wang CY, Alfano CM, Blackburn GL, Pollack M, McTiernan A

While in vitro models allow more controlled and complex study designs compared with in vivo models, cultured muscle cell models typically have low endogenous GLUT4 expression [115,116], often lack a mature transverse tubule system [117], and do not recapitulate in vivo insulin responses to the same degree as the 3T3-L1 adipocyte

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