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237,238 In an observational study involving 852 individuals who underwent polysomnography, about half reported experiencing the first night effect, roughly 20% showed a reverse first night effect (meaning they slept better than usual), and the remaining 30% reported no significant change in their sleep

10 Twin studies have revealed significantly higher concordance between monozygotic twins (63%) than between dizygotic twins (23%)

Furthermore, microglia-specific Atg7 deletion leads to the intracellular accumulation of phagocytosed myelin and exacerbates multiple sclerosislike pathology, distinguishing its role from Ulk1 -dependent pathways [102]

Xiong X, Zuo Y, Cheng L, Yin Z, Hu T, Guo M, Han Z, Ge X, Li W, Wang Y, Wang D, Wang C, Zhang L, Zhang Y, Liu Q, Chen F, Lei P (2022) Modafinil reduces neuronal pyroptosis and cognitive decline after sleep deprivation