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The TME of NSCLC contains a large number of TAMs which influence tumor progression and patient prognosis, and specifically, M2 TAMs were shown to induce tumor aggressiveness and proliferation in NSCLC [63, 64]

Weight loss is the most effective treatment for fatty liver disease, with studies showing that losing 710% of body weight can significantly reduce hepatic steatosis

Key Takeaway: Glutathione is a naturally occurring molecule that supports cellular defense and detoxification, but internal levels often decrease as we age or face environmental stress

Taken together, we propose that chronic GSH depletion induces redox activation of the AMPK pathway that may serve as the central link triggering mechanisms that prevent alcohol-induced liver injury (as illustrated in Fig